Buyer's guide

    Looking for a GC-VUV alternative?

    If you're evaluating GC-VUV (gas chromatography with vacuum ultraviolet detection) and balking at the helium dependency, the vacuum-purged optical path or the capex, you're not alone. Most labs end up choosing a vacuum-UV detector for one specific capability — absolute, isomer-level absorbance — and accept the operational tax that comes with it. INSCAN's GC-UV platform gives you the same physics in a simpler envelope. This page is a short, plain-spoken guide to whether GC-UV is the right replacement for your GC-VUV workflow.

    Six reasons labs migrate from GC-VUV to INSCAN GC-UV

    No vacuum, no purge gas

    INSCAN's GC-UV optics operate above 155 nm in ambient atmosphere. There is no vacuum chamber to maintain and no continuous nitrogen purge of the optical path.

    Run on nitrogen or hydrogen

    Methods are validated on N₂, H₂ and He. Drop your dependence on global helium supply without re-validating against a different detector class.

    Lower capex and TCO

    A simpler optical assembly and standard deuterium / tungsten sources keep both acquisition and service costs well below typical vacuum-UV instruments.

    Same Beer–Lambert quantitation

    INSCAN preserves the absolute, response-factor-free quantitation that GC-VUV users already trust — only across the 155–330 nm band where most aromatic and heteroaromatic fingerprints live.

    Isomer-level identification

    Positional and structural isomers (o-/m-/p-xylene, cis/trans alkenes, phenol substitution patterns) resolve cleanly on full UV spectra, not retention time alone.

    Multi-vendor service ecosystem

    INSCAN ships from Europe with EU-based support, certified ISO 9001:2015 and ISO/IEC 27001:2022, and a partner network that does not rely on a single North-American supplier.

    When GC-UV is not the right swap

    We try to be honest. If your method is locked to ASTM D8071 PIONA classification, or if you depend on the 125–155 nm window for permanent-gas work, conventional GC-VUV remains the technically correct tool. INSCAN starts at ~155 nm, which is enough for the vast majority of pharmaceutical, petrochemical and environmental analytes — but not all. Read the full GC-VUV vs GC-UV comparison before you decide.

    Next step: a 5-minute fit assessment

    Our client portal walks you through a short questionnaire — analyte class, matrix, throughput, regulatory framework — and returns a verdict on whether INSCAN GC-UV is a credible replacement for your current GC-VUV method, with a recommended INSCAN configuration if the answer is yes.